Wa tiyo ki jami ma ki lwongo ni cookies me medo rom pa tic ni. Ka i mede ki neno kabedo man, in iye ni wa tiyo ki jami ma ki lwongo ni cookies. Ngec mukene.
Ka i dii "Yer gin mo keken", in iye ni ki gwoko jami ma ki lwongo ni cookies i cim ni me medo rwom me wot i kabedowa, nyamo kit ma kitiyo kwede ki kabedowa, ki miiyo kony me miiyo jami ma pe ki culu, ma dano twero donyo iye. Ngec mukene.
Temo lac ma yot twero nyutu two ma ki lwongo ni Alzheimer, ma weko yub me temo dano mapol? Kwan manyen me Frontiers in Aging Neuroscience nyutu man. Lutim kwed ni gu temo dul dano mapol ma tye ki two ma ki lwongo ni Alzheimer ma pek ne pat pat ki dano ma kom gi yot ma tam gi tye maber me neno apoka poka ma tye i kom lanyut me lac.
Gin gunongo ni formic acid i lac obedo lanyut ma mako rweny pa tam ki twero nyutu acaki me two ma ki lwongo ni Alzheimer. Yoo ma tye me nongo two ma ki lwongo ni Alzheimer wel ne tek, pe yot, ki pe kitwero temo ne kare ki kare. Man tere ni pol pa lutwo ki nongo gi ka kare okato pi nongo kony maber. Ento, yat ma pe kelo peko, ma wel ne yot, ki ma yot pi yat ma ki lwongo ni formic acid twero bedo gin ma ludactale tye ka penyo pire pi neno yat ma pud peya ocakke.
"Two ma ki lwongo ni Alzheimer obedo two ma rii ki ma pe nen, ma nyutu ni twero dongo ki rii pi mwaki mapol ma peya peko me tam nen," lucoc ni owaco. "Acakki me two ni time ma peya acakki me two ma pe twero dwogo cen, ma en aye wang dirica maber pi kony ki cango. Pi meno, kwan madit pi two ma ki lwongo ni Alzheimer i kom jo mutegi mitte."
Pi meno, ka kony oyoto pire tek, pingo pe wa bedo ki yub me temo two ma ki lwongo ni Alzheimer ma pud peya ocakke? Peko ni tye i yoo ma ludaktari gitye ka tic kwede i kare ni. Man tye iye positron emission tomography me wic, ma wel ne tek ki keto lutwo i lyeto. Tye jami ma ki temo ma twero nyutu two ma ki lwongo ni Alzheimer's, ento gi miito ni ki kwany remo ma ki keto i kom dano onyo ki kwanyo remo ki i cing dano me nongo pii ma aa ki i wic, ma lutwo twero bedo ka juku.
Ento, temo lac pe kelo peko ki bene yot, ma miyo bedo ber pi temo dano mapol. Kadi bed ni lutim kwed gu nongo lanyut me two ma ki lwongo ni Alzheimer i lac, pe tye mo ma rwate me nongo two man ma pud peya ocakke, ma nyutu ni yoo maber me nongo kony me cango two man pud peya ki nongo.
Lutim kwed ma tye i nge kwan manyen ni gu kwano gin mo ma ki lwongo ni formaldehyde ma calo gin ma nyutu two ma ki lwongo ni Alzheimer. Ento, tye kabedo me medo rwom me nongo two oyotoyot. I kwan manyen ni, gin gu keto cwiny gi i kom formate, gin ma ki lwongo ni formaldehyde metabolite, me neno ka tiyo maber calo lanyut.
Dano ma romo 574 gubedo i yub man, ki jo ma gubedo i yub man onongo gubedo lutic ma gitye ki yotkom maber nyo onongo gitye ki rwom me dongo mapat pat me two, cakke ki i rweny pa tam nio wa i two ma pe gik. Lutim kwed ni gu kwano lac ki remo pa dano ma gubedo i yub man ki gu timo kwedo tam gi.
Kwano ni onongo ni rwom me acid ma tye i lac onongo tye malo tutwal i kin dul dano ma tye ki two Alzheimer ki onongo rwate ki rweny pa tam ka kiporo ki jo ma kom gi yot, medo ki dul ma onongo tye ki rweny pa tam macon. Man nyutu ni formic acid twero bedo calo gin ma nyutu two ma ki lwongo ni Alzheimer i acaki.
I yo me miti, i kare ma lutim kwed ni gu kwano rwom me formate i lac ki lanyut me remo pa Alzheimer, gunongo ni gitwero tito rwom me two ma latwo tye ka kato ki iye maber. Ento, kwedo ngec mukene mitte me niang wat ma tye i kin two ma ki lwongo ni Alzheimer ki formic acid.
"Acid ma ki lwongo ni formic acid i lac onyutu ni ber tutwal pi temo two ma ki lwongo ni Alzheimer," lucoc ni owaco. "Temo lanyut me lac pi two ma ki lwongo ni Alzheimer yot ki wel ne yot ki omyera ki ket i yub me temo yot kom pa jo mutegi."
Wang, Y. ki luwote. (2022) Neno jami ma ki lwongo ni urinary formic acid ma calo gin manyen ma twero nyutu two ma ki lwongo ni Alzheimer. Anyim i lok ma mako wic pa dano ma mwaka gi dit. doi.org/10.3389/fnagi.2022.1046066.
Nying: mwaka, two ma ki lwongo ni Alzheimer's, lanyut me kwo, remo, wic, two ma rii, two ma rii, jami ma mako wic, two ma mako wic, daktar, formaldehyde, neurology, positron emission tomography, kwedo ngec, tomography, urinalysis
I Pittcon 2023 i Philadelphia, Pennsylvania, wa penyo lapwony Joseph Wang, ngat ma oloyo Ralph N. Adams Prize i mwaka ni i Analytical Chemistry, i kom kit ma jami ma ki lwongo ni biosensor twero tic kwede.
I lok man, wa nyamo lok ma mako kwanyo remo ki kit ma twero bedo gin ma konyo me pwonyo jami ma nyutu two oyotoyot ki Mariana Leal, Latela pa gurup i Owlstone Medical.
Ma calo dul me neno wa me SLAS US 2023, wa nyamo lok ma mako ot yat me anyim ki kit ma obi nen kwede ki Luigi Da Via, latela pa dul ma yubu jami ma ki temo i GSK.
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